AstraZeneca's Imfinzi (durvalumab) has been approved in the European Union and the UK for an additional dosing option, a 1,500mg fixed dose every four weeks, in locally advanced, unresectable non-small cell lung cancer (NSCLC) in adults whose tumours express PD-L1 on at least 1% of tumour cells and whose disease has not progressed following platinum-based chemoradiation therapy (CRT).
Lung cancer is the leading cause of cancer death and 80-85% of patients with lung cancer have NSCLC.1-3 Approximately one third of patients are diagnosed in the Stage III setting and the majority of these have unresectable tumours and are treated with curative intent.3-5
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