Mike4 wrote:EXCEPT.... Israel used mostly Pfizer and UK has used mostly AZ, AIUI, and the data does not distinguish, does it?
Just curious really.
Dr Campbells figures are only for the Pfizer vaccine.
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Mike4 wrote:EXCEPT.... Israel used mostly Pfizer and UK has used mostly AZ, AIUI, and the data does not distinguish, does it?
Just curious really.
Mike4 wrote:9873210 wrote:So if protection wanes starting at the date of the second dose we would expect the UK curve to be three months behind the Israel curve. I.e. the UK overall would be the same as Israel in April because almost everybody in the UK received their second dose in April or later. And that's what we see.
Note that I am not saying whether or not the interval matters. I am saying this data does not allow us to say either way.
EXCEPT.... Israel used mostly Pfizer and UK has used mostly AZ, AIUI, and the data does not distinguish, does it?
Just curious really.
9873210 wrote:
Also, Do you have numbers on which vaccines have been used in the UK? My sources are all silent on that point.
Mike4 wrote:9873210 wrote:
Also, Do you have numbers on which vaccines have been used in the UK? My sources are all silent on that point.
Only the poll results on here:
viewtopic.php?t=28125
9873210 wrote:Also, Do you have numbers on which vaccines have been used in the UK? My sources are all silent on that point.
88V8 wrote:Moderna highlighting booster likelihood...
New data announced by Moderna is showing its mRNA COVID-19 vaccine remains significantly effective after six months. However, the company does note that a possible reduction in efficacy in the face of the new Delta variant indicates a likely need for third dose boosters later in 2021.
Also.. The company has also announced full enrolment for Phase 1 trialling of its next generation mRNA COVID-19 vaccine. This new version of the vaccine is designed to target different parts of the coronavirus spike protein in the hope of getting ahead of any new viral variants. This new vaccine formulation is also reportedly stable at warmer temperatures than its previous candidate, meaning it could be stored safely in refrigerators.
And vaccines for those aged 6 months up are being trialled.
https://investors.modernatx.com/news-re ... -financial
Some say this is the drugs companies trying to generate revenue.
The WHO would prefer that the third world has priority over first world topups.
What will BoJo decide.....
V8
“There are two dimensions to this immunity — antibodies [which] decline over time, but the second, very important dimension of vaccination is the so-called T-cells. They tend to protect people against severe disease, but they also provide durability,” Soriot explained.
“With the technology we use, we have very high production of T-cells. We’re hoping we can have a durable vaccine that protects for a long period of time. So whether we will need a third booster or not is not clear yet, only time will tell.”
88V8 wrote:The WHO would prefer that the third world has priority over first world topups.
What will BoJo decide.....
V8
88V8 wrote:To less than universal acclaim, it is reported that the US will offer boosters to anyone whose second dose was <8 months ago.
“I’m truly disappointed,” says infectious disease expert Muge Cevik on Twitter. “This decision in not justifiable at all looking at this data. We are going to use up millions of doses to reduce the small risk of mild infections in fully protected people with a tiny risk of hospitalization, while most of the world waits for a first dose.”
The govt view is that “The available data make very clear that protection against SARS-CoV-2 infection begins to decrease over time following the initial doses of vaccination, and in association with the dominance of the Delta variant, we are starting to see evidence of reduced protection against mild and moderate disease. Based on our latest assessment, the current protection against severe disease, hospitalization, and death could diminish in the months ahead, especially among those who are at higher risk or were vaccinated during the earlier phases of the vaccination rollout. For that reason, we conclude that a booster shot will be needed to maximize vaccine-induced protection and prolong its durability.”
The programme is scheduled as from September 20th.
https://newatlas.com/health-wellbeing/coronavirus-vaccine-boosters-all-americans-experts-divided/?utm_source=New+Atlas+Subscribers&utm_campaign=e198c1da07-EMAIL_CAMPAIGN_2021_08_19_08_09&utm_medium=email&utm_term=0_65b67362bd-e198c1da07-92456261
V8
ursaminortaur wrote:88V8 wrote:To less than universal acclaim, it is reported that the US will offer boosters to anyone whose second dose was <8 months ago.
That should be greater than ( > ) 8 months not less than ( < ) 8 months.
9873210 wrote:88V8 wrote:The WHO would prefer that the third world has priority over first world topups.
What will BoJo decide.....
V8
It is not an either/or decision.
Vaccination in middle, including lower middle, income countries is moving along. Lower middle income countries are about 4 months behind high income countries. Not entirely equitable, but probably far better than you thought. The most important factor for lower middle income countries is to keep the supply up and the cost bounded. Get Novavax approved. Stop dissing AstraZeneca and Janssen. Don't shut down vaccine production when the UK etc. reach 200% coverage.
Where things are not progressing is the Low income countries. These are about 9% of the worlds population. Making significant progress here would be a rounding error in the first world's, or the UK's, or China's, vaccine supply. It won't be a problem of vaccine supply, it's the usual problems of getting somebody to pay, and, in some countries, getting things organized with a barely functioning government. It may not matter how many doses are available if there is a civil war, or if plane loads of vaccine rot at an airport.
So yes there are problems and a moral imperative, but WHO is not describing the world that actually exists.
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